KD-Validated Anti-CCDC93 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
---|---|
Primary Accession | Q567U6 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 24GB7985 |
Calculated MW | Predicted, 73 kDa, observed, 73 kDa |
Gene Name | CCDC93 |
Aliases | CCDC93; Coiled-Coil Domain Containing 93; Coiled-Coil Domain-Containing Protein 93; FLJ10996 |
Immunogen | Recombinant protein of human CCDC93 |
Gene ID | 54520 |
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Other Names | Coiled-coil domain-containing protein 93, CCDC93 |
Name | CCDC93 |
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Function | Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels (PubMed:37172566, PubMed:38459129). The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:25355947, PubMed:28892079). Involved in copper- dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947). |
Cellular Location | Early endosome. |

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