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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-ATP5C1 Mouse Monoclonal Antibody
KD-Validated Anti-ATP5C1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | P36542 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB7990 |
| Calculated MW | Predicted, 33 kDa, observed, 33 kDa |
| Gene Name | ATP5F1C |
| Aliases | ATP5F1C; ATP Synthase F1 Subunit Gamma; ATP5CL1; ATP5C1; ATP5C; ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, Gamma Polypeptide 1; ATP Synthase Subunit Gamma, Mitochondrial; F-ATPase Gamma Subunit; Mitochondrial ATP Synthase, Gamma Subunit 1; ATP Synthase Gamma Chain, Mitochondrial |
| Immunogen | Recombinant protein of human ATP5C1 |
| Gene ID | 509 |
|---|---|
| Other Names | ATP synthase F(1) complex subunit gamma, mitochondrial, ATP synthase F1 subunit gamma {ECO:0000312|HGNC:HGNC:833}, F-ATPase gamma subunit, ATP5F1C (HGNC:833) |
| Name | ATP5F1C (HGNC:833) |
|---|---|
| Function | Subunit gamma, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:37244256). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the central stalk subunit delta, is essential for the biogenesis of F(1) catalytic part of the ATP synthase complex namely in the formation of F1 assembly intermediate (PubMed:29499186). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P05631}; Peripheral membrane protein {ECO:0000250|UniProtKB:P05631}; Matrix side {ECO:0000250|UniProtKB:P05631} |
| Tissue Location | Isoform Heart is expressed specifically in the heart and skeletal muscle, which require rapid energy supply. Isoform Liver is expressed in the brain, liver and kidney. Isoform Heart and Isoform Liver are expressed in the skin, intestine, stomach and aorta |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2016
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