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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-CTDSP2 Mouse Monoclonal Antibody
KD-Validated Anti-CTDSP2 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | O14595 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB8045 |
| Calculated MW | Predicted, 31 kDa, observed, 35 kDa |
| Gene Name | CTDSP2 |
| Aliases | CTDSP2; CTD Small Phosphatase 2; SCP2; OS4; Nuclear LIM Interactor-Interacting Factor 2; NLI-Interacting Factor 2; Small CTD Phosphatase 2; PSR2; CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase 2; Carboxy-Terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 2; Conserved Gene Amplified In Osteosarcoma; Small C-Terminal Domain Phosphatase 2; Protein OS-4; EC 3.1.3.16; NIF |
| Immunogen | Recombinant protein of human CTDSP2 |
| Gene ID | 10106 |
|---|---|
| Other Names | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2, 3.1.3.16, Nuclear LIM interactor-interacting factor 2, NLI-interacting factor 2, Protein OS-4, Small C-terminal domain phosphatase 2, Small CTD phosphatase 2, SCP2, CTDSP2, NIF2, OS4, SCP2 |
| Name | CTDSP2 |
|---|---|
| Synonyms | NIF2, OS4, SCP2 |
| Function | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. |
| Cellular Location | Nucleus. |
| Tissue Location | Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI2020
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