KD-Validated Anti-GALE Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q14376 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 24GB13050 |
Calculated MW | Predicted, 38 kDa, observed, 34 kDa |
Gene Name | GALE |
Aliases | GALE; UDP-Galactose-4-Epimerase; UDP-Glucose 4-Epimerase; SDR1E1; Short Chain Dehydrogenase/Reductase Family 1E, Member 1; UDP-N-Acetylgalactosamine 4-Epimerase; UDP-N-Acetylglucosamine 4-Epimerase; Galactose-4-Epimerase, UDP-; UDP-GalNAc 4-Epimerase; UDP-GlcNAc 4-Epimerase; Galactowaldenase; EC 5.1.3.2; Epididymis Secretory Sperm Binding Protein; UDP Galactose-4'-Epimerase; UDP-Galactose 4-Epimerase; EC 5.1.3.7; EC 5.1.3 47; THC13 |
Immunogen | Recombinant protein of human GALE |
Gene ID | 2582 |
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Other Names | UDP-glucose 4-epimerase, 5.1.3.2, Galactowaldenase, UDP-N-acetylgalactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, 5.1.3.7, UDP-galactose 4-epimerase, GALE (HGNC:4116) |
Name | GALE (HGNC:4116) |
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Function | Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. |

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