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KD-Validated Anti-PDE1B Mouse Monoclonal Antibody

Mouse monoclonal antibody

     
  • WB - KD-Validated Anti-PDE1B Mouse Monoclonal Antibody AGI2081
    Western blotting analysis using anti-phosphodiesterase 1B antibody (Cat#AGI2081). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-phosphodiesterase 1B antibody (Cat#AGI2081, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody respectively.
    detail
  • WB - KD-Validated Anti-PDE1B Mouse Monoclonal Antibody AGI2081
    Western blotting analysis using anti-phosphodiesterase 1B antibody (Cat#AGI2081). Phosphodiesterase 1B expression in wild-type (WT) and phosphodiesterase 1B (PDE1B) shRNA knockdown (KD) HeLa cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-phosphodiesterase 1B antibody (Cat#AGI2081, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody respectively.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q01064
Reactivity Rat, Human
Clonality Monoclonal
Isotype Mouse IgG2b
Clone Names 24GB13240
Calculated MW Predicted, 61 kDa, observed, 61 kDa
Gene Name PDE1B
Aliases PDE1B; Phosphodiesterase 1B; PDES1B; Dual Specificity Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B; Phosphodiesterase 1B, Calmodulin-Dependent; 63 KDa Cam-PDE; EC 3.1.4.17; Cam-PDE 1B; Presumed 63kDa Form Of The Type 1 Cyclic Nucleotide Phosphodiesterase Family Known As PDE1B; Calcium/Calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B; Calcium/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase; Epididymis Secretory Sperm Binding Protein Li 79p; Calmodulin-Stimulated Phosphodiesterase PDE1B1; HEL-S-79p; EC 3.1.4; PDE1B1
Immunogen Recombinant protein of human PDE1B
Additional Information
Gene ID 5153
Other Names Dual specificity calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 3.1.4.17, 63 kDa Cam-PDE, PDE1B (HGNC:8775), PDES1B
Protein Information
Name PDE1B (HGNC:8775)
Synonyms PDES1B
Function Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15260978, PubMed:8855339, PubMed:9419816). Has a preference for cGMP as a substrate (PubMed:9419816).
Cellular Location Cytoplasm, cytosol.
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI2081
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