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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-HERPUD1 Mouse Monoclonal Antibody
KD-Validated Anti-HERPUD1 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q15011 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG2a |
| Clone Names | 24GB14035 |
| Calculated MW | Predicted, 44 kDa, observed, 54 kDa |
| Gene Name | HERPUD1 |
| Aliases | HERPUD1; Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1; HERP; KIAA0025; Mif1; SUP; Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1; Homocysteine-Responsive Endoplasmic Reticulum-Resident Ubiquitin-Like Domain Member 1 Protein; Methyl Methanesulfonate (MMF)-Inducible Fragment Protein 1; omocysteine-Inducible Endoplasmic Reticulum Stress-Inducible Ubiquitin-Like Domain Member 1 Protein; MMS-Inducible; MIF1 |
| Immunogen | Recombinant protein of human HERPUD1 |
| Gene ID | 9709 |
|---|---|
| Other Names | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, Methyl methanesulfonate (MMF)-inducible fragment protein 1, HERPUD1, HERP, KIAA0025, MIF1 |
| Name | HERPUD1 |
|---|---|
| Synonyms | HERP, KIAA0025, MIF1 |
| Function | Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16289116, PubMed:28827405). Could enhance presenilin- mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI2169
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