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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-PIK3R4 Rabbit Monoclonal Antibody
KD-Validated Anti-PIK3R4 Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | Q99570 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB325 |
| Calculated MW | Predicted, 153 kDa, observed, 149 kDa |
| Gene Name | PIK3R4 |
| Aliases | PIK3R4; Phosphoinositide-3-Kinase Regulatory Subunit 4; VPS15; P150; Phosphoinositide 3-Kinase Regulatory Subunit 4; Phosphoinositide 3-Kinase Adaptor Protein; PI3-Kinase Regulatory Subunit 4; PI3-Kinase P150 Subunit; EC 2.7.11.1; Phosphoinositide-3-Kinase, Regulatory Subunit 4, P150; Phosphoinositide-3-Kinase, Regulatory Subunit 4; Phosphatidylinositol 3-Kinase-Associated P150 |
| Immunogen | A synthesized peptide derived from human PIK3R4 |
| Gene ID | 30849 |
|---|---|
| Other Names | Phosphoinositide 3-kinase regulatory subunit 4, PI3-kinase regulatory subunit 4, 2.7.11.1, PI3-kinase p150 subunit, Phosphoinositide 3-kinase adaptor protein, PIK3R4, VPS15 {ECO:0000303|PubMed:23878393} |
| Name | PIK3R4 |
|---|---|
| Synonyms | VPS15 {ECO:0000303|PubMed:23878393} |
| Function | Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). |
| Cellular Location | Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor. Note=As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes. Localizes also to discrete punctae along the ciliary axoneme (By similarity) {ECO:0000250|UniProtKB:Q8VD65, ECO:0000305} |
| Tissue Location | Ubiquitously expressed. |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2215
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