KD-Validated Anti-FNTA Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC |
|---|---|
| Primary Accession | P49354 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB1570 |
| Calculated MW | Predicted, 44 kDa; observed, 44 kDa |
| Gene Name | FNTA |
| Aliases | FNTA; Farnesyltransferase, CAAX Box, Subunit Alpha; Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha; PGGT1A; PTAR2; FPTA; Protein Prenyltransferase Alpha Subunit Repeat Containing 2; Ras Proteins Prenyltransferase Subunit Alpha; Farnesyltransferase, CAAX Box, Alpha; GGTase-I-Alpha; FTase-Alpha; Type I Protein Geranyl-Geranyltransferase Alpha Subunit; Type I Protein Geranyl-Geranyltransferase Subunit Alpha; Farnesyl-Protein Transferase Alpha-Subunit; CAAX Farnesyltransferase Subunit Alpha; EC 2.5.1.58; EC 2.5.1.59 |
| Immunogen | A synthesized peptide derived from human FNTA |
| Gene ID | 2339 |
|---|---|
| Other Names | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, 2.5.1.58, 2.5.1.59, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA |
| Name | FNTA |
|---|---|
| Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. |

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