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KD-Validated Anti-FNTA Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-FNTA Rabbit Monoclonal Antibody AGI2237
    Western blotting analysis using anti-FNTA antibody (Cat#65441). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-FNTA antibody (Cat#65441, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
    detail
  • WB - KD-Validated Anti-FNTA Rabbit Monoclonal Antibody AGI2237
    Western blotting analysis using anti-FNTA antibody (Cat#65441). FNTA expression in wild-type (WT) and FNTA shRNA knockdown (KD) HeLa cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-FNTA antibody (Cat#65441, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
    detail
  • FC - KD-Validated Anti-FNTA Rabbit Monoclonal Antibody AGI2237
    Flow cytometric analysis of AVEN expression in HepG2 cells using anti-AVEN antibody (Cat#5505, 1:2,000). Green, isotype control; red, AVEN.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC
Primary Accession P49354
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 25GB1570
Calculated MW Predicted, 44 kDa; observed, 44 kDa
Gene Name FNTA
Aliases FNTA; Farnesyltransferase, CAAX Box, Subunit Alpha; Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha; PGGT1A; PTAR2; FPTA; Protein Prenyltransferase Alpha Subunit Repeat Containing 2; Ras Proteins Prenyltransferase Subunit Alpha; Farnesyltransferase, CAAX Box, Alpha; GGTase-I-Alpha; FTase-Alpha; Type I Protein Geranyl-Geranyltransferase Alpha Subunit; Type I Protein Geranyl-Geranyltransferase Subunit Alpha; Farnesyl-Protein Transferase Alpha-Subunit; CAAX Farnesyltransferase Subunit Alpha; EC 2.5.1.58; EC 2.5.1.59
Immunogen A synthesized peptide derived from human FNTA
Additional Information
Gene ID 2339
Other Names Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, 2.5.1.58, 2.5.1.59, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
Protein Information
Name FNTA
Function Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic- aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2237
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