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TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone CA72/145 ]
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, FC, IP |
|---|---|
| Other Accession | 182875, Not Known |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgG1, kappa |
| Clone Names | CA72/145 |
| Calculated MW | 220kDa |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
|---|---|
| Precautions | TAG-72 / CA72.4 (Tumor-Associated Glycoprotein) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
References
Lottich SC et. al. Breast Cancer Research and Treatment, 1985, 6(1):49-56. | Thor A et. al. Cancer Research, 1986, 46(6):3118-24
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