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Anti-Interferon alpha-2 (IFNA2) Antibody

Mouse Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, FC, E
Primary Accession P01563
Other Accession 211575
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names N27
Calculated MW 21578 Da
Additional Information
Gene ID 3440
Other Names Alpha 2a interferon; IFN alpha; IFN-alpha-2; IFNA; IFNA2; IFNA2B; Interferon alpha 2a; Interferon alpha 2b; Interferon alpha-2; Interferon alpha-A; LeIF2; LeIFA
Application Note ELISA (For coating, order Ab without BSA);Blocking Activity (Order Ab without Azide);Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1ug/ml); Optimal dilution for a specific application should be determined.
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
PrecautionsAnti-Interferon alpha-2 (IFNA2) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IFNA2
Synonyms IFNA2A, IFNA2B, IFNA2C
Function Produced by macrophages, IFN-alpha have antiviral activities.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

Recognizes a protein of 16-27kDa, identified as human interferon-�II) (IFN-(II). Its epitope maps between aa43-53 of the IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). Epitopes of N27 and N39 MAb s are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-�II) is one of the two distinct families (I and II) of human IFN-. The  interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

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$ 219.00
$ 499.00
Cat# AH13309-20
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