DBP antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q10586 |
Other Accession | NM_001352, NP_001343 |
Reactivity | Human, Mouse, Rat, Pig, Sheep, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 34kDa |
Gene ID | 1628 |
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Alias Symbol | DABP |
Other Names | D site-binding protein, Albumin D box-binding protein, Albumin D-element-binding protein, Tax-responsive enhancer element-binding protein 302, TaxREB302, DBP |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DBP antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | DBP antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DBP |
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Function | This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity |
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Provided below are standard protocols that you may find useful for product applications.
References
Smith,J.S.,et al.,(2000) Genomics 64(1),44-50Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Publications:Okazaki, H. et al. Circadian regulation of mTOR by the ubiquitin pathway in renal cell carcinoma. Cancer Res. 74, 543-51 (2014). WB, Human, Pig, Horse, Guinea pig, Sheep, Dog, Bovine, Mouse, Rat24253377Nakabayashi, H. et al. Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β gene expression in pancreatic islet β-cells. Biochem. Biophys. Res. Commun. 434, 370-5 (2013). WB, Human, Pig, Horse, Guinea pig, Sheep, Dog, Bovine, Mouse, Rat23567972
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