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ASGR2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P07307 |
| Other Accession | NM_001181, NP_001172 |
| Reactivity | Human, Pig |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34kDa |
| Gene ID | 433 |
|---|---|
| Alias Symbol | HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2 |
| Other Names | Asialoglycoprotein receptor 2, ASGP-R 2, ASGPR 2, C-type lectin domain family 4 member H2, Hepatic lectin H2, HL-2, ASGR2, CLEC4H2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-ASGR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | ASGR2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ASGR2 |
|---|---|
| Synonyms | CLEC4H2 |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N- acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Cellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Location | Expressed exclusively in hepatic parenchymal cells. |
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Provided below are standard protocols that you may find useful for product applications.
References
Yik,J.H.,et al., (2002) J.Biol.Chem.277(43),40844-40852Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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