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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Cacnb2 Antibody - middle region
Cacnb2 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8VGC3 |
| Other Accession | NM_053851, NP_446303 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Pig, Horse, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 66kDa |
| Gene ID | 116600 |
|---|---|
| Alias Symbol | Cacnlb2 |
| Other Names | Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Cacnb2, Cacnlb2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Cacnb2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Cacnb2 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Cacnb2 |
|---|---|
| Synonyms | Cacnlb2 |
| Function | Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (PubMed:1370480, PubMed:12042350). Plays a role in shifting voltage dependencies of activation and inactivation of the channel (PubMed:1370480, PubMed:12042350). May modulate G protein inhibition (PubMed:11604404, PubMed:12042350, PubMed:1370480). May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force (By similarity). Involved in membrane targeting of the alpha-1 subunit CACNA1C (By similarity). |
| Cellular Location | Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side |
| Tissue Location | Highly expressed in heart and brain, and at lower levels in lung. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI10855
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