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KCNH3 antibody - middle region
Rabbit Polyclonal Antibody
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9ULD8 |
| Other Accession | NM_012284, NP_036416 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 117kDa |
| Gene ID | 23416 |
|---|---|
| Alias Symbol | BEC1, ELK2, KIAA1282, Kv12.2 |
| Other Names | Potassium voltage-gated channel subfamily H member 3, Brain-specific eag-like channel 1, BEC1, Ether-a-go-go-like potassium channel 2, ELK channel 2, ELK2, Voltage-gated potassium channel subunit Kv12.2, KCNH3, KIAA1282 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-KCNH3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | KCNH3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNH3 (HGNC:6252) |
|---|---|
| Synonyms | KIAA1282 |
| Function | Pore-forming (alpha) subunit of a voltage-gated inwardly rectifying potassium channel (PubMed:10455180). Charactherized by a fast rate of activation during depolarization followed by a rapid inactivation at much more depolarized value causing inward rectification due to a C-type inactivation mechanism (PubMed:10455180). Exhibits a rapid recovery from inactivation (PubMed:10455180). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9WVJ0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9WVJ0} Note=Expression on the cell membrane requires at least one of the three glycosylation sites to carry a sugar chain irrespective of their positions. {ECO:0000250|UniProtKB:Q9WVJ0} |
| Tissue Location | Detected only in brain, in particular in the telencephalon (PubMed:10455180). Detected in the cerebral cortex, occipital pole, frontal and temporal lobe, putamen, amygdala, hippocampus and caudate nucleus (PubMed:10455180) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Gutman,G.A., (2005) Pharmacol. Rev. 57 (4), 473-508 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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