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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Rbbp5 antibody - N-terminal region
Rbbp5 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8BX09 |
| Other Accession | NM_172517, NP_766105 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59kDa |
| Gene ID | 213464 |
|---|---|
| Alias Symbol | 4933411J24Rik, C330016J05 |
| Other Names | Retinoblastoma-binding protein 5, RBBP-5, Rbbp5 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Rbbp5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Rbbp5 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Rbbp5 |
|---|---|
| Function | In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (PubMed:21335234). Does not affect ES cell self-renewal (PubMed:21335234). Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3 (By similarity). Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity). In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity). |
| Cellular Location | Nucleus. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI11428
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