GPR177 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q5T9L3 |
Other Accession | NM_001002292, NP_001002292 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Chicken |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 62kDa |
Gene ID | 79971 |
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Alias Symbol | C1orf139, EVI, FLJ23091, MGC131760, MGC14878, MRP, WLS, GPR177 |
Other Names | Protein wntless homolog, Integral membrane protein GPR177, Protein evenness interrupted homolog, EVI, Putative NF-kappa-B-activating protein 373, WLS, C1orf139, GPR177 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-GPR177 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | GPR177 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | WLS |
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Synonyms | C1orf139, GPR177 |
Function | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins (PubMed:34587386). Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity). |
Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Note=Co-localizes with the adaptin AP2A2 at distinct punctae. |

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Provided below are standard protocols that you may find useful for product applications.
References
Gregory,S.G.,(2006)Nature441(7091),315-321ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.

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