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SGPP2 antibody - C-terminal region
Rabbit Polyclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q8IWX5 |
| Other Accession | XP_001128702 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Horse |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 37kDa |
| Gene ID | 130367 |
|---|---|
| Alias Symbol | FLJ39004, SPP2 |
| Other Names | Sphingosine-1-phosphate phosphatase 2, SPPase2, Spp2, hSPP2, 3.1.3.-, Sphingosine-1-phosphatase 2, SGPP2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-SGPP2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SGPP2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SGPP2 (HGNC:19953) |
|---|---|
| Function | Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (PubMed:12411432). Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (By similarity). May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling (PubMed:17113265). Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Expressed strongly in kidney and heart, followed by brain, colon, small intestine and lung. Not detected in skeletal muscle, thymus, spleen, liver, placenta, and peripheral blood leukocytes. |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 339.00
Cat# AI12614
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