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PCDH12 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9NPG4 |
| Other Accession | NM_016580, NP_057664 |
| Reactivity | Human, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Rat, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 126kDa |
| Gene ID | 51294 |
|---|---|
| Alias Symbol | VE-cadherin-2, VECAD2 |
| Other Names | Protocadherin-12, Vascular cadherin-2, Vascular endothelial cadherin-2, VE-cad-2, VE-cadherin-2, PCDH12 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-PCDH12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | PCDH12 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCDH12 (HGNC:8657) |
|---|---|
| Function | Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions (By similarity). Acts as a regulator of cell migration, probably via increasing cell- cell adhesion (PubMed:21402705). Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions (By similarity). Unable to bind to catenins, weakly associates with the cytoskeleton (By similarity). |
| Cellular Location | [Protocadherin-12]: Cell membrane; Single-pass type I membrane protein. Cell junction {ECO:0000250|UniProtKB:O55134} |
| Tissue Location | Expressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression (PubMed:11063261). Prominent expression in the spleen (PubMed:11063261). Present in villous and extravillous trophoblast (at protein level) (PubMed:21402705). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Clark,H.F.,(2003)GenomeRes.13(10),2265-2270ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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