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St6galnac1 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - St6galnac1 antibody - C-terminal region AI12798

    WB Suggested Anti-St6galnac1 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Pancreas
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9QZ39
Other Accession NM_011371, NP_035501
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 61kDa
Additional Information
Gene ID 20445
Alias Symbol Siat7a
Other Names Alpha-N-acetylgalactosaminide alpha-2, 6-sialyltransferase 1, 2.4.99.3, GalNAc alpha-2, 6-sialyltransferase I, ST6GalNAc I, ST6GalNAcI, Sialyltransferase 7A, SIAT7-A, St6galnac1, Siat7a
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-St6galnac1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSt6galnac1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name St6galnac1 {ECO:0000312|MGI:MGI:1341826}
Synonyms Siat7a
Function Protein sialyltransferase specifically expressed in goblet cells that plays a key role in intestinal host-commensal homeostasis (PubMed:35303419). Conjugates sialic acid with an alpha-2-6 linkage to N-acetylgalactosamine (GalNAc) glycan chains linked to serine or threonine in glycoproteins (PubMed:10788794). Catalyzes the formation of the sialyl-Tn (S-Tn) antigen, an antigen found in intestinal goblet cells (PubMed:35303419). Protein sialylation in globlet cells is essential for mucus integrity and is required to protect the intestinal mucus against excessive bacterial proteolytic degradation (PubMed:35303419).
Cellular Location Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9NSC7}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9NSC7}
Tissue Location Submaxillary gland, mammary gland, spleen and colon.
Research Areas
Citations (0)
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$ 389.00
Cat# AI12798
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