Naa60 Antibody - N-terminal region
Rabbit Polyclonal Antibody
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- BACKGROUND
Application
| WB |
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Primary Accession | Q3MHC1 |
Other Accession | NM_001014226, NP_001014248 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Goat, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26kDa |
Gene ID | 363545 |
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Alias Symbol | MGC124897, RGD1308915 |
Other Names | N-alpha-acetyltransferase 60, 2.3.1.48, 2.3.1.88, GNAT acetyltransferase, N-acetyltransferase 15, NatF catalytic subunit, Naa60, Nat15 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Naa60 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Naa60 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Naa60 |
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Synonyms | Nat15 |
Function | N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N- terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences. |
Cellular Location | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9H7X0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H7X0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9H7X0}. Note=Probably forms a intramembrane hairpin-like structure in the membrane. {ECO:0000250|UniProtKB:Q9H7X0} |
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