HIST1H1T antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P22492 |
Other Accession | NM_005323, NP_005314 |
Reactivity | Human, Rabbit, Pig, Dog |
Predicted | Human, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22kDa |
Gene ID | 3010 |
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Alias Symbol | H1FT, H1t, MGC163222, dJ221C16.2 |
Other Names | Histone H1t, Testicular H1 histone, HIST1H1T, H1FT, H1T |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HIST1H1T antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | HIST1H1T antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | H1-6 (HGNC:4720) |
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Function | Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes (PubMed:26757249). Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination (PubMed:26757249). Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration (Probable). |
Cellular Location | Nucleus. Chromosome. |
Tissue Location | Testis-specific. |
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Provided below are standard protocols that you may find useful for product applications.
References
Drabent B.,et al.Gene 103:263-268(1991).
Koppel D.A.,et al.J. Cell. Biochem. 54:219-230(1994).
Marzluff W.F.,et al.Genomics 80:487-498(2002).
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