CCNDBP1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O95273 |
Other Accession | NM_037370, NP_411241 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Pig, Horse, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26kDa |
Gene ID | 23582 |
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Alias Symbol | DIP1, GCIP, HHM |
Other Names | Cyclin-D1-binding protein 1, Grap2 and cyclin-D-interacting protein, Human homolog of Maid, CCNDBP1, DIP1, GCIP, HHM |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CCNDBP1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | CCNDBP1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCNDBP1 |
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Synonyms | DIP1, GCIP, HHM |
Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. |
Cellular Location | Cytoplasm. Nucleus. |
Tissue Location | Ubiquitously expressed. Expression is down- regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas |
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