FTSJD1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8IYT2 |
Other Accession | NM_018348, NP_060818 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Yeast, Bovine, Guinea Pig, Dog |
Predicted | Rat, Rabbit, Chicken, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 88kDa |
Gene ID | 55783 |
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Alias Symbol | AFT, MTr2, FTSJD1 |
Other Names | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2, 2.1.1.296, Cap methyltransferase 2, Cap2 2'O-ribose methyltransferase 2, HMTr2, MTr2, FtsJ methyltransferase domain-containing protein 1, Protein adrift homolog, CMTR2, AFT, FTSJD1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-FTSJD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | FTSJD1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CMTR2 |
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Synonyms | AFT, FTSJD1 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs. |
Cellular Location | Nucleus. Cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zan Q.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Werner M.,et al.Nucleic Acids Res. 39:4756-4768(2011).
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