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RAB22A antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P35285 |
| Other Accession | NM_020673, NP_065724 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 22kDa |
| Gene ID | 19334 |
|---|---|
| Alias Symbol | MGC16770 |
| Other Names | Ras-related protein Rab-22A, Rab-22, Rab-14, Rab22a, Rab22 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-RAB22A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | RAB22A antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Rab22a |
|---|---|
| Synonyms | Rab22 |
| Function | Plays a role in endocytosis and intracellular protein transport (PubMed:19759177, PubMed:27718357). Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF- mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (By similarity). |
| Cellular Location | Endosome membrane; Lipid-anchor. Cell membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Early endosome Late endosome {ECO:0000250|UniProtKB:P51154}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9UL26}. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q9UL26}. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. {ECO:0000250|UniProtKB:Q9UL26} |
| Tissue Location | Detected in brain and heart, and at lower levels in lung and spleen. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Kussmann S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Chavrier P.,et al.Gene 112:261-264(1992).
Olkkonen V.M.,et al.J. Cell Sci. 106:1249-1261(1993).
Zhu H.,et al.Mol. Biol. Cell 20:4720-4729(2009).
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