|Other Accession||NM_024039, NP_076944|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine|
|Predicted||Human, Mouse, Rat, Rabbit, Bovine|
|Alias Symbol||2510025F08Rik, KNTC2AP, MGC2488, MTW1, hMis12|
|Other Names||Protein MIS12 homolog, MIS12 (HGNC:24967)|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-MIS12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MIS12 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108).|
|Cellular Location||Chromosome, centromere, kinetochore Note=Associated with the kinetochore.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Goshima G.,et al.J. Cell Biol. 160:25-39(2003).
Obuse C.,et al.Nat. Cell Biol. 6:1135-1141(2004).
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