|Other Accession||NM_144939, NP_659188|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2|
|Other Names||Fibroblast growth factor receptor substrate 3, FGFR substrate 3, FRS2-beta, Frs3, Frs2b|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Frs3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Frs3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.|
|Cellular Location||Membrane; Lipid-anchor.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Zhou L.,et al.Mol. Biol. Rep. 30:15-25(2003).
Ong S.-H.,et al.Mol. Cell. Biol. 20:979-989(2000).
Avery A.W.,et al.Cell. Signal. 19:177-184(2007).
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