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Wipf1 Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Wipf1 Antibody - N-terminal region AI14317

    WB Suggested Anti-Wipf1 Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Small Intestine
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q6IN36
Other Accession NM_057192, NP_476540
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Additional Information
Gene ID 117538
Alias Symbol Waspip, Wip
Other Names WAS/WASL-interacting protein family member 1, Wiskott-Aldrich syndrome protein-interacting protein, WASP-interacting protein, Wipf1, Waspip, Wip
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Wipf1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsWipf1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Wipf1
Synonyms Waspip, Wip
Function Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. Plays a role in the formation of cell ruffles (By similarity). May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation.
Cellular Location Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Cell projection, ruffle Note=Vesicle surfaces and along actin tails. Colocalizes with actin stress fibers. When coexpressed with WASL, no longer associated with actin filaments but accumulated in perinuclear and cortical areas like WASL
Tissue Location Isoforms were differentially expressed. One isoform was ubiquitously expressed, another was muscle-specific and another was expressed in the liver, heart and testis
Citations (0)
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References

Vetterkind S.,et al.J. Biol. Chem. 277:87-95(2002).

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$ 389.00
Cat# AI14317
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