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Wnt3a antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P27467 |
| Other Accession | NM_009522, NP_033548 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 38kDa |
| Gene ID | 22416 |
|---|---|
| Alias Symbol | vt, Wnt-3a |
| Other Names | Protein Wnt-3a, Wnt3a, Wnt-3a |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Wnt3a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Wnt3a antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Wnt3a |
|---|---|
| Synonyms | Wnt-3a |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (PubMed:26902720). Required for normal embryonic mesoderm development and formation of caudal somites (PubMed:8299937). Required for normal morphogenesis of the developing neural tube (PubMed:8299937). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) (PubMed:26902720). |
| Cellular Location | Secreted, extracellular space, extracellular matrix. Secreted |
| Tissue Location | Dorsal portion of the neural tube (developing roof plate), and mesenchyme tissue surrounding the umbilical veins |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Roelink H.,et al.Genes Dev. 5:381-388(1991).
Tanaka K.,et al.Eur. J. Biochem. 267:4300-4311(2000).
Willert K.,et al.Nature 423:448-452(2003).
Zhang X.,et al.Cell 149:1565-1577(2012).
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