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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   USP9X antibody - C-terminal region   

USP9X antibody - C-terminal region

Rabbit Polyclonal Antibody

  • IHC - USP9X antibody - C-terminal region AI14384
    mouse 3T3 s
  • WB - USP9X antibody - C-terminal region AI14384

    Sample Type: 1. total HeLa cell extract (100ug)2. total HeLa cell extract incubated with HA-UbVME (100ug)3. Rat Liver cytosolic extract (100ug)4. Rat Liver cytosolic extract incubated with HA-UbVME (100ug)Primary Dilution: 1:1000
    Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image
    Submitted by: Andreia CarvalhoIBMC-OBF, Portugal
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q93008
Other Accession NM_001039590, NP_001034679
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 292kDa
Additional Information
Gene ID 8239
Alias Symbol DFFRX, FAF, FAM
Other Names Probable ubiquitin carboxyl-terminal hydrolase FAF-X,, Deubiquitinating enzyme FAF-X, Fat facets in mammals, hFAM, Fat facets protein-related, X-linked, Ubiquitin thioesterase FAF-X, Ubiquitin-specific protease 9, X chromosome, Ubiquitin-specific-processing protease FAF-X, USP9X, DFFRX, FAM, USP9
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-USP9X antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsUSP9X antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name USP9X (HGNC:12632)
Synonyms DFFRX, FAM, USP9
Function Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'- linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed:16322459, PubMed:18254724, PubMed:19135894, PubMed:24607389). Regulates cellular clock function by enhancing the protein stability and transcriptional activity of the core circadian protein ARNTL/BMAL1 via its deubiquitinating activity (PubMed:29626158).
Cellular Location Cytoplasm. Cell projection, growth cone
Tissue Location Widely expressed in embryonic and adult tissues.
Research Areas
Citations ( 0 )


Jones M.H.,et al.Hum. Mol. Genet. 5:1695-1701(1996).
Jones M.H.,et al.Hum. Mol. Genet. 6:334-335(1996).
Ross M.T.,et al.Nature 434:325-337(2005).
Yu W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).

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$ 389.00
Cat# AI14384
Availability: 2-3 days
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