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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Scg3 antibody - C-terminal region   

Scg3 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Scg3 antibody - C-terminal region AI14397

    WB Suggested Anti-Scg3 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Small Intestine
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P47867
Other Accession NM_001164790, NP_001158262
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 55kDa
Additional Information
Gene ID 20255
Alias Symbol 1B1075, AI385542, Chgd, SgIII
Other Names Secretogranin-3, Secretogranin III, SgIII, Scg3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Scg3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsScg3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Scg3
Function Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:16219686). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (PubMed:12388744). May also play a role in angiogenesis (PubMed:28330905). Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P47868}; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. {ECO:0000250|UniProtKB:P47868}
Tissue Location Expressed in various brain areas, with highest levels in the arcuate nucleus and the lateral hypothalamic area, as well as the paraventricular nucleus and the ventromedial hypothalamus (at protein level).
Research Areas
Citations (0)

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References

Dopazo A.,et al.J. Mol. Neurosci. 4:225-233(1993).
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Hosaka M.,et al.Mol. Biol. Cell 13:3388-3399(2002).
Tanabe A.,et al.J. Clin. Endocrinol. Metab. 92:1145-1154(2007).

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$ 389.00
Cat# AI14397
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