Snap29 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9Z2P6 |
Other Accession | NM_053810, NP_446262 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
Predicted | Human, Rat, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 29kDa |
Alias Symbol | Gs32, MGC105273 |
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Other Names | Synaptosomal-associated protein 29, SNAP-29, Golgi SNARE of 32 kDa, Gs32, Soluble 29 kDa NSF attachment protein, Vesicle-membrane fusion protein SNAP-29, Snap29 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Snap29 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Snap29 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Snap29 {ECO:0000250|UniProtKB:O95721} |
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Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
Cellular Location | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane {ECO:0000250|UniProtKB:O95721}; Peripheral membrane protein. Cell projection, cilium membrane {ECO:0000250|UniProtKB:O95721}; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic Localizes to the ciliary pocket from where the cilium protrudes {ECO:0000250|UniProtKB:O95721} |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
References
Wong S.H.,et al.Mol. Biol. Cell 10:119-134(1999).
Lubec G.,et al.Submitted (APR-2007) to UniProtKB.
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