|Other Accession||NM_009008, NP_033034|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Chicken, Bovine, Guinea Pig|
|Alias Symbol||AI323801, AI452260|
|Other Names||Ras-related C3 botulinum toxin substrate 2, Protein EN-7, p21-Rac2, Rac2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Rac2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Rac2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.|
|Cellular Location||Cytoplasm. Membrane; Lipid-anchor. Note=Membrane-associated when activated|
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Shirsat N.V.,et al.Oncogene 5:769-772(1990).
Carninci P.,et al.Science 309:1559-1563(2005).
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