CNTFR antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
 
| Application  
 | WB | 
|---|---|
| Primary Accession | P26992 | 
| Other Accession | NM_001842, NP_001833 | 
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Sheep, Horse, Bovine, Guinea Pig, Dog | 
| Predicted | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Calculated MW | 41kDa | 
| Gene ID | 1271 | 
|---|---|
| Alias Symbol | MGC1774 | 
| Other Names | Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha, CNTFR | 
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | 
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-CNTFR antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. | 
| Precautions | CNTFR antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. | 
| Name | CNTFR | 
|---|---|
| Function | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1 (PubMed:26858303). Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1 (PubMed:19386761). | 
| Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. | 
| Tissue Location | Nervous system and skeletal muscle. | 

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Provided below are standard protocols that you may find useful for product applications.
References
Davis S.,et al.Science 253:59-63(1991).
Valenzuela D.M.,et al.Genomics 25:157-163(1995).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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