|Other Accession||NM_014205, NP_055020|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Rabbit, Pig, Bovine, Guinea Pig|
|Alias Symbol||C11orf5, FON|
|Other Names||Zinc finger HIT domain-containing protein 2, Protein FON, ZNHIT2, C11orf5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ZNHIT2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZNHIT2 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (PubMed:28561026). Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8 (PubMed:28561026). May play a role in regulating the composition of the U5 snRNP complex (PubMed:28561026).|
|Tissue Location||Low expression in most tissues; highly expressed in testis.|
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Provided below are standard protocols that you may find useful for product applications.
Lemmens I.H.,et al.Mamm. Genome 11:78-80(2000).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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