|Other Accession||NM_031957, NP_114163|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Goat, Sheep, Horse, Bovine, Guinea Pig|
|Predicted||Human, Mouse, Rat|
|Alias Symbol||KAP1.5, KRTAP1.5, MGC126604|
|Other Names||Keratin-associated protein 1-5, High sulfur keratin-associated protein 1.5, Keratin-associated protein 1.5, KRTAP1-5, KAP1.5, KRTAP1.5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-KRTAP1-5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||KRTAP1-5 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.|
|Tissue Location||Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone|
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Provided below are standard protocols that you may find useful for product applications.
Rogers M.A.,et al.J. Biol. Chem. 276:19440-19451(2001).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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