|Other Accession||NM_023104, EDM13551|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Other Names||Acetoacetyl-CoA synthetase, 22.214.171.124, Aacs|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Aacs antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Aacs antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development.|
|Cellular Location||Cytoplasm, cytosol.|
|Tissue Location||Abundant in male subcutaneous white adipose tissue after weaning. In white adipose tissue, it is preferentially detected in mature adipocytes but not in preadipocytes. The expression in primary preadipocytes increases during the adipocyte differentiation In brain, it is expressed in the midbrain, pons/medulla, cerebral cortex, hippocampus and cerebellum. The expression in the cerebellum is restricted primarily to glial cells, while in the cerebral cortex, it is restricted to neuronal cells.|
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Provided below are standard protocols that you may find useful for product applications.
Iwahori A.,et al.FEBS Lett. 466:239-243(2000).
Ohnuki M.,et al.Biochim. Biophys. Acta 1729:147-153(2005).
Yamasaki M.,et al.Biochem. Biophys. Res. Commun. 335:215-219(2005).
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