|Other Accession||NM_024551, NP_078827|
|Reactivity||Human, Mouse, Rat, Rabbit, Goat, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||ACDCR2, FLJ21432, MGC4640, PAQR2|
|Other Names||Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2, PAQR2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ADIPOR2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ADIPOR2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Localized to the cell membrane and intracellular organelles|
|Tissue Location||Ubiquitous (PubMed:16044242). Highly expressed in skeletal muscle, liver and placenta (PubMed:12802337). Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung (PubMed:12802337)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Tang Y.T.,et al.J. Mol. Evol. 61:372-380(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yamauchi T.,et al.Nature 423:762-769(2003).
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