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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DOHH antibody - N-terminal region   

DOHH antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - DOHH antibody - N-terminal region AI14583

    WB Suggested Anti-DOHH Antibody Titration: 1.0 μg/ml
    Positive Control: MDA-MB-435S Whole CellDOHH is strongly supported by BioGPS gene expression data to be expressed in Human MDA-MB435 cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BU89
Other Accession NM_031304, NP_112594
Reactivity Human, Mouse, Rat, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 33kDa
Additional Information
Gene ID 83475
Alias Symbol HLRC1, MGC4293, hDOHH
Other Names Deoxyhypusine hydroxylase {ECO:0000255|HAMAP-Rule:MF_03101}, hDOHH, {ECO:0000255|HAMAP-Rule:MF_03101}, Deoxyhypusine dioxygenase {ECO:0000255|HAMAP-Rule:MF_03101}, Deoxyhypusine monooxygenase {ECO:0000255|HAMAP-Rule:MF_03101}, HEAT-like repeat-containing protein 1, DOHH {ECO:0000255|HAMAP-Rule:MF_03101}, HLRC1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-DOHH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsDOHH antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DOHH {ECO:0000255|HAMAP-Rule:MF_03101, ECO:0000312|HGNC:HGNC:28662}
Function Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF- 5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function (By similarity).
Research Areas
Citations (0)

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Grimwood J.,et al.Nature 428:529-535(2004).
Kim Y.S.,et al.J. Biol. Chem. 281:13217-13225(2006).
Park J.-H.,et al.Proc. Natl. Acad. Sci. U.S.A. 103:51-56(2006).
Vu V.V.,et al.Proc. Natl. Acad. Sci. U.S.A. 106:14814-14819(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 389.00
Cat# AI14583
Availability: 2-3 days
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