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DHPS antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P49366 |
| Other Accession | NM_013406, NP_037538 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Horse, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35kDa |
| Gene ID | 1725 |
|---|---|
| Alias Symbol | MIG13, DS, DHS |
| Other Names | Deoxyhypusine synthase, DHS, 2.5.1.46, DHPS, DS |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-DHPS antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | DHPS antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DHPS |
|---|---|
| Synonyms | DS |
| Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue (PubMed:30661771). This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Joe Y.A.,et al.J. Biol. Chem. 270:22386-22392(1995).
Bevec D.,et al.FEBS Lett. 378:195-198(1996).
Yan Y.P.,et al.Biochem. J. 315:429-434(1996).
Mantuano E.,et al.Gene 215:153-157(1998).
Yu W.,et al.Genome Res. 7:353-358(1997).
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