|Other Accession||NM_008831, NP_032857|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Chicken, Bovine, Dog|
|Alias Symbol||BAP32, Bap32|
|Other Names||Prohibitin, B-cell receptor-associated protein 32, BAP 32, Phb|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Phb antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Phb antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:23241883, PubMed:24856930, PubMed:29324904). Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner (PubMed:24947361). Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity).|
|Cellular Location||Mitochondrion inner membrane. Nucleus Cell membrane. Cytoplasm|
|Tissue Location||Widely expressed in different tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Terashima M.,et al.EMBO J. 13:3782-3792(1994).
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Lubec G.,et al.Submitted (MAR-2007) to UniProtKB.
Coates P.J.,et al.Exp. Cell Res. 265:262-273(2001).
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