|Other Accession||NM_014470, NP_055285|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Bovine, Dog|
|Alias Symbol||ARHS, FLJ42294, RHO6, RHOS|
|Other Names||Rho-related GTP-binding protein Rho6, Rho family GTPase 1, Rnd1, RND1, RHO6|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RND1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RND1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton|
|Tissue Location||Mostly expressed in brain and liver.|
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Provided below are standard protocols that you may find useful for product applications.
Nobes C.D.,et al.J. Cell Biol. 141:187-197(1998).
Tanaka S.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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