|Other Accession||NM_007051, NP_008982|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||CGI-03, FLJ37524, HFAF1s, UBXD12, UBXN3A, hFAF1|
|Other Names||FAS-associated factor 1, hFAF1, UBX domain-containing protein 12, UBX domain-containing protein 3A, FAF1, UBXD12, UBXN3A|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FAF1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FAF1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ubiquitin-binding protein (PubMed:19722279). Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation (PubMed:26842564). Potentiates but cannot initiate FAS-induced apoptosis (By similarity).|
|Tissue Location||Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ryu S.-W.,et al.Biochem. Biophys. Res. Commun. 262:388-394(1999).
Ding J.B.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Boldyreff B.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
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