|Other Accession||NM_139248, NP_640341|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||AH, LPDLR, PLA1B, mPA-PLA1, LAH2, ARWH2|
|Other Names||Lipase member H, LIPH, 3.1.1.-, LPD lipase-related protein, Membrane-associated phosphatidic acid-selective phospholipase A1-alpha, mPA-PLA1 alpha, Phospholipase A1 member B, LIPH, LPDLR, MPAPLA1, PLA1B|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LIPH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LIPH antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||LPDLR, MPAPLA1, PLA1B|
|Function||Hydrolyzes specifically phosphatidic acid (PA) to produce 2- acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).|
|Cellular Location||Secreted. Cell membrane; Peripheral membrane protein|
|Tissue Location||Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region.|
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Provided below are standard protocols that you may find useful for product applications.
Sonoda H.,et al.J. Biol. Chem. 277:34254-34263(2002).
Jin W.,et al.Genomics 80:268-273(2002).
Kazantseva A.,et al.Science 314:982-985(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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