|Other Accession||NM_001195556, NP_001182485|
|Alias Symbol||CSIG, DKFZP564M182, L12, MGC138433, MGC142259, PBK1, UTP30|
|Other Names||Clathrin interactor 1, Clathrin-interacting protein localized in the trans-Golgi region, Clint, Enthoprotin, Epsin-4, Epsin-related protein, EpsinR, CLINT1, ENTH, EPN4, EPNR, KIAA0171|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-RSL1D1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RSL1D1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ENTH, EPN4, EPNR, KIAA0171|
|Function||Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.|
|Cellular Location||Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network|
|Tissue Location||Ubiquitously expressed at low to intermediate levels.|
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Provided below are standard protocols that you may find useful for product applications.
Wasiak S.,et al.J. Cell Biol. 158:855-862(2002).
Hong W.,et al.Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
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