|Other Accession||NM_014988, NP_055803|
|Reactivity||Human, Mouse, Rat, Rabbit, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Dog|
|Alias Symbol||DKFZp434I0312, DKFZp686A01247, DKFZp686B2470, DKFZp686G18243, DKFZp686G2094, DKFZp781C1754, DKFZp781I1455, LIMCH1A, LMO7B, MGC72127|
|Other Names||LIM and calponin homology domains-containing protein 1, LIMCH1, KIAA1102|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LIMCH1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LIMCH1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Actin stress fibers-associated protein that activates non- muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration.|
|Cellular Location||Cytoplasm, cytoskeleton, stress fiber|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hillier L.W.,et al.Nature 434:724-731(2005).
Olsen J.V.,et al.Cell 127:635-648(2006).
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