|Other Accession||NM_145201, NP_660202|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rabbit, Horse, Bovine|
|Other Names||Nicotinate phosphoribosyltransferase, NAPRTase, 126.96.36.199, FHA-HIT-interacting protein, Nicotinate phosphoribosyltransferase domain-containing protein 1, NAPRT, FHIP, NAPRT1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-NAPRT1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NAPRT1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate (PubMed:17604275, PubMed:21742010, PubMed:26042198). Helps prevent cellular oxidative stress via its role in NAD biosynthesis (PubMed:17604275).|
|Cellular Location||Cytoplasm, cytosol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Hara N.,et al.J. Biol. Chem. 282:24574-24582(2007).
Huang C.-H.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
Beausoleil S.A.,et al.Nat. Biotechnol. 24:1285-1292(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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