|Other Accession||NM_181716, NP_859067|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||3110013H01Rik, CENP-V, PRR6, p30|
|Other Names||Centromere protein V, CENP-V, Nuclear protein p30, Proline-rich protein 6, CENPV, PRR6|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CENPV antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CENPV antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for distribution of pericentromeric heterochromatin in interphase nuclei and for centromere formation and organization, chromosome alignment and cytokinesis.|
|Cellular Location||Chromosome, centromere, kinetochore. Nucleus Cytoplasm, cytoskeleton, spindle Note=Enriched at the nuclear periphery and around the nucleolus (PubMed:12196509). In mitotic cells, localizes to kinetochores from prometaphase to metaphase (PubMed:18772885). At anaphase onset, transfers to the spindle midzone and then to the mid-body in telophase and cytokinesis (PubMed:18772885)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Zheng H.,et al.Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
Cronshaw J.M.,et al.J. Cell Biol. 158:915-927(2002).
Tadeu A.M.B.,et al.EMBO J. 27:2510-2522(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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