|Other Accession||NM_000655, NP_000646|
|Alias Symbol||CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1|
|Other Names||L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L, SELL, LNHR, LYAM1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SELL antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SELL antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28489325, PubMed:28011641). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in B-cell lines and T-lymphocytes.|
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Provided below are standard protocols that you may find useful for product applications.
Siegelman M.H.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5562-5566(1989).
Tedder T.F.,et al.J. Exp. Med. 170:123-133(1989).
Camerini D.,et al.Nature 342:78-82(1989).
Bowen B.R.,et al.J. Cell Biol. 109:421-427(1989).
Ord D.C.,et al.J. Biol. Chem. 265:7760-7767(1990).
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