C16orf70 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9BSU1 |
Other Accession | NM_025187, NP_079463 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46kDa |
Gene ID | 80262 |
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Alias Symbol | C16orf6, FLJ12076, LIN10, lin-10 |
Other Names | UPF0183 protein C16orf70, C16orf70, C16orf6 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C16orf70 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C16orf70 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PHAF1 (HGNC:29564) |
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Synonyms | C16orf6, C16orf70 |
Function | Plays a regulatory role in autophagic activity. In complex with BCAS3, associates with the autophagosome formation site during both non-selective and selective autophagy. |
Cellular Location | Cytoplasm. Preautophagosomal structure. Note=The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner. |
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Provided below are standard protocols that you may find useful for product applications.
References
Lee Y.M.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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