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Sos1 Antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Sos1 Antibody - N-terminal region AI14944

    Host: Rabbit
    Target Name: Sos1
    Sample Tissue: Mouse Spleen lysates
    Antibody Dilution: 1.0μg/ml
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q62245
Other Accession NM_009231, NP_033257
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 151kDa
Additional Information
Gene ID 20662
Alias Symbol 4430401P03Rik, 9630010N06, AI449023
Other Names Son of sevenless homolog 1, SOS-1, mSOS-1, Sos1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Sos1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSos1 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Sos1
Function Promotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (By similarity). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (PubMed:10499589, PubMed:11524436).
Tissue Location Expressed in most embryonic and adult tissues.
Research Areas
Citations (0)
citation

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References

Bowtell D.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:6511-6515(1992).
Scita G.,et al.Nature 401:290-293(1999).
Scita G.,et al.J. Cell Biol. 154:1031-1044(2001).
Munton R.P.,et al.Mol. Cell. Proteomics 6:283-293(2007).
Villen J.,et al.Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).

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$ 389.00
Cat# AI14944
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